Rekombinanter ZEB1 Antikörper (C-Term)

Produktnummer ABIN7795625

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch ZEB1 in WB, FACS und IP. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Rekombinanter ZEB1 Antikörper (C-Term) (ABIN7795625)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: BLR102H

Produktdetails anti-ZEB1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR102H] - BSA-Free

Aufreinigung: Purified

Immunogen: Between 1074 and C-terminus

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1

Hintergrund: ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.

Gen-ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation